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Symbol
Name
ID
E2f1
E2F transcription factor 1
MGI:101941
Phenotype annotations related to endocrine/exocrine glands
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
abnormal exocrine pancreas morphology
abnormal salivary gland morphology
abnormal parotid gland morphology
abnormal submandibular gland morphology
decreased salivation
salivary gland inflammation
endocrine/exocrine gland phenotype
abnormal gland morphology
abnormal pancreatic islet morphology
abnormal pancreatic beta cell morphology
decreased pancreatic islet number
small pancreatic islets
increased thymus weight
enlarged thymus
increased thymocyte number
abnormal exorbital lacrimal gland morphology
abnormal pancreas morphology
decreased pancreas weight
seminiferous tubule degeneration
increased Leydig cell number
decreased testis weight
testicular atrophy
increased T cell derived lymphoma incidence
decreased insulin secretion
insulitis
Availability Mouse Genotype
E2f1tm1.1Dgj/E2f1tm1.1Dgj *
E2f1tm1Meg/E2f1tm1Meg
E2f1tm1Njd/E2f1tm1Njd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory